Figure 6. SULT2B1b expression correlates with numerous TNF-related genes in human patients.
(A) Gene co-expression indicates SULT2B1 negatively correlates with TNF, CD40LG, TRADD, and TRAF2 in bone marrow-derived metastatic prostate cancer samples from individuals with no prior treatment. (B) Co-expression of SULT2B1 with NFKB1, FADD, and DR4 determines significant negative correlations with each of these genes in lymph node-derived CRPC samples. (C) Gene co-expression of SULT2B1 with RANKL demonstrates a strong positive correlation in bone marrow-derived prostate cancer samples. Pearson correlation coefficients (r) and p-values determined by a permutation test (p) are indicated for each correlation plot. Dots indicate samples obtained from individual patients.