Table 2.
Mean (SD) for D2‐like receptor availability (BPND) across two studies using [18F]Fallypride PET
| Region | Overall BPND M (SD) | Study 1 BPND M (SD) | Study 2 BPND M (SD) | Study mean difference [95% CI] |
|---|---|---|---|---|
| Ventral striatum | 37.16 (8.01) | 39.21 (7.66) | 33.33 (7.27) | −5.89 [−8.6, −3.17] |
| Putamen | 33.02 (4.87) | 32.7 (5.09) | 33.63 (4.41) | 0.93 [−0.77, 2.64] |
| Caudate nucleus | 26.9 (5.2) | 25.92 (5.15) | 28.64 (4.87) | 2.71 [0.91, 4.51] |
| Pallidum | 14.83 (3.47) | 15.84 (3.28) | 13.13 (3.12) | −2.72 [−3.86, −1.57] |
| Subcallosal area | 9.23 (3.88) | 9.86 (3.79) | 8.03 (3.82) | −1.83 [−3.27, −0.39] |
| Amygdala | 3.02 (0.65) | 3.2 (0.64) | 2.69 (0.56) | −0.51 [−0.72, −0.3] |
| Insula | 2.44 (0.64) | 2.33 (0.57) | 2.64 (0.7) | 0.32 [0.08, 0.56] |
| Thalamus | 2.43 (0.39) | 2.4 (0.34) | 2.47 (0.47) | 0.07 [−0.09, 0.22] |
| Anterior temporal lobe, lateral | 1.67 (0.48) | 1.56 (0.37) | 1.86 (0.59) | 0.3 [0.12, 0.49] |
| Anterior temporal lobe, medial | 1.64 (0.45) | 1.5 (0.35) | 1.89 (0.5) | 0.39 [0.23, 0.56] |
| Fusiform gyrus | 1.62 (0.39) | 1.55 (0.35) | 1.75 (0.44) | 0.19 [0.04, 0.35] |
| Superior temporal gyrus, anterior | 1.44 (0.52) | 1.26 (0.4) | 1.75 (0.56) | 0.49 [0.3, 0.67] |
| Middle and inferior temporal gyrus | 1.4 (0.45) | 1.29 (0.36) | 1.59 (0.54) | 0.31 [0.13, 0.48] |
| Hippocampus | 1.34 (0.43) | 1.47 (0.44) | 1.11 (0.3) | −0.36 [−0.48, −0.23] |
| Straight gyrus | 1.23 (0.44) | 1.05 (0.34) | 1.52 (0.43) | 0.47 [0.32, 0.62] |
| Medial orbital gyrus | 1.19 (0.38) | 1.03 (0.29) | 1.45 (0.38) | 0.42 [0.3, 0.55] |
| Subgenual frontal cortex | 1.01 (0.55) | 0.72 (0.35) | 1.53 (0.43) | 0.81 [0.66, 0.97] |
| Posterior orbital gyrus | 0.94 (0.39) | 0.78 (0.31) | 1.19 (0.37) | 0.41 [0.28, 0.54] |
| Superior temporal gyrus, posterior | 0.82 (0.39) | 0.7 (0.32) | 1.05 (0.42) | 0.35 [0.21, 0.49] |
| Posterior temporal lobe | 0.81 (0.35) | 0.72 (0.31) | 0.98 (0.35) | 0.25 [0.13, 0.38] |
| Parahippocampal and ambient gyri | 0.8 (0.27) | 0.71 (0.18) | 0.96 (0.33) | 0.26 [0.15, 0.36] |
| Lateral orbital gyrus | 0.64 (0.4) | 0.48 (0.25) | 0.93 (0.45) | 0.45 [0.3, 0.59] |
| Anterior orbital gyrus | 0.63 (0.37) | 0.46 (0.25) | 0.93 (0.37) | 0.47 [0.35, 0.59] |
| Inferiolateral remainder of parietal lobe | 0.61 (0.42) | 0.43 (0.3) | 0.92 (0.42) | 0.49 [0.35, 0.63] |
| Pre‐subgenual frontal cortex | 0.59 (0.24) | 0.52 (0.2) | 0.74 (0.25) | 0.22 [0.14, 0.31] |
| Cingulate gyrus, anterior | 0.55 (0.27) | 0.41 (0.19) | 0.8 (0.2) | 0.4 [0.32, 0.47] |
| Inferior frontal gyrus | 0.44 (0.37) | 0.25 (0.21) | 0.79 (0.34) | 0.54 [0.43, 0.65] |
| Superior frontal gyrus | 0.4 (0.34) | 0.2 (0.14) | 0.78 (0.27) | 0.58 [0.5, 0.67] |
| Middle frontal gyrus | 0.34 (0.35) | 0.18 (0.19) | 0.64 (0.38) | 0.46 [0.34, 0.58] |
| Postcentral gyrus | 0.32 (0.4) | 0.11 (0.11) | 0.68 (0.46) | 0.57 [0.42, 0.71] |
| Superior parietal gyrus | 0.31 (0.35) | 0.14 (0.16) | 0.6 (0.39) | 0.46 [0.34, 0.59] |
| Cingulate gyrus, posterior | 0.31 (0.27) | 0.21 (0.19) | 0.47 (0.3) | 0.26 [0.17, 0.36] |
| Precentral gyrus | 0.23 (0.27) | 0.08 (0.09) | 0.48 (0.29) | 0.4 [0.3, 0.49] |
Significant differences are denoted in bold.