Table 1.

Uni-SNP and multi-SNP models with prostate cancer risk

		Min<Maj		Uni-SNP		Multi-SNPa
SNP	Gene	(MAF)b	Modec	OR (95% CI)b	p-value	OR (95% CI)b	p-value
rs16902359	CASC11	C<T (0.46)	Rec	0.76 (0.66–0.88)	2.8 × 10−4	0.79 (0.68–0.92)	0.002
rs12680047	MYC:PVT1	T<C (0.24)	Dom	0.84 (0.74–0.94)	3.5 × 10−3	0.87 (0.77–0.99)	0.029
rs9642880	CASC11	G<T (0.25)	Add	0.87 (0.79-0.96)	3.8 × 10−3	-	-

^aall models adjusted for study site and first four principal components. Model only considered SNP individual effects.

^bMin/Maj: minor and major allele; MAF: minor allele frequency; OR: odds ratio, CI: confidence interval

^cAdd: Additive; Dom: dominant; Rec: recessive