Figure. Annual prevalence of active AE, by age.
Local polynomial smoothed plot with shading indicating the 95% CIs generated from cross-sectional calculations of the prevalence of active AE at each age using Stata 15 (StataCorp). Active disease was defined by a visit or prescription code during each year of follow-up among patients who previously met the definition of AE (characterized by ≥1 of the following diagnosis codes: M111.00 [atopic dermatitis/eczema], M1120.0 [infantile eczema], M113.00 [flexural eczema], M114.00 [allergic/intrinsic eczema], and M12z100 [eczema not otherwise specified]) and were assigned ≥2 treatment codes for any AE-related therapy on separate dates (4). AE = atopic eczema.