Table 2.
Descriptive statistics for the four groups for analysis
| SCZ-died | SCZ-alive | Control-died | Control-alive | |
|---|---|---|---|---|
| N | 126 | 63 | 127 | 62 |
| Males, N (%) | 76 (60.3) | 38 (60.3) | 71 (55.9) | 40 (63.5) |
| Age at sampling, years | 58 (53, 61) | 56 (51, 60) | 68 (61, 74) | 57.5 (51, 61) |
| Age at death, years | 62.3 (56.3, 65) | N/A | 71.2 (65.4, 78.4) | N/A |
| Follow-up timea | 3.95 (2.9, 5.5) | 6(5, 6) | 4.1 (2.8, 5.4) | 5(5, 6) |
| Inpatient hospitalizationsb | 13.5 (7.3, 24) | 13 (7, 25.5) | 0 | 0 |
| Outpatient hospitalizationsb | 9.5 (5, 16.8) | 12(5, 19) | 0 | 0 |
| Antipsychotic prescriptions | 140 (40.5, 247) | 205 (90.5, 341) | 0 | 0 |
| Smoking score | 6.2 (1.1, 9.6) | 2.3 (−1.8, 7.1) | −0.74 (−3.5, 3.4) | −2.3 (−4.6, 0.2) |
| Hannum | ||||
| mAge | 53.7 (49.8, 56.7) | 51.2 (48.4, 56.1) | 60.7 (55.3, 65.9) | 51.7 (49.1, 56.7) |
| mAge acceleration | −0.17 (−2.5, 2.1) | −0.40 (−2.3, 1.1) | 0.04 (−2.2, 2.2) | 0.20 (−2.8, 2.5) |
| Horvath | ||||
| mAge | 57.1 (52.6, 61.5) | 55.2 (51.9, 58.6) | 64.6 (58.5, 69.9) | 57.2 (53.4, 60.8) |
| mAge acceleration | 0.31 (−3.2, 2.9) | −0.27 (−2.9, 1.5) | −0.35 (−2.8, 2.5) | 0.29 (−1.9, 2.7) |
| Levine | ||||
| mAge | 50.6 (45.9, 55.4) | 47.8 (43.7, 53.3) | 58.9 (52.4, 64.9) | 48.2 (43.2, 52.4) |
| mAge acceleration | 0.72 (−2.6, 3.6) | −0.88 (−3.4, 2.5) | 0.04 (−3.5, 3.5) | −1.5 (−4.5, 3.1) |
For continuous variables, the median and interquartile range are reported; for categorical variables, the number of individuals and percent are reported. For the methylation age (mAge), the value is reported in years aFor those who died, time between sampling and death; for alive, this is time between sampling and last follow-up bHospitalizations with discharge diagnoses of SCZ or schizoaffective disorder. N/A not applicable