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. 2019 Jun 4;9:159. doi: 10.1038/s41398-019-0493-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The figure depicts exemplary MRI images (a) and the mean total brain volume and corresponding standard deviation of ABA and control animals at three different time points (b): before starvation, after starvation and after refeeding. Analysis of MRI brain volume in the ABA and control animals was performed using a linear mixed effects model with a random intercept and unstructured covariance. Pairwise comparisons were evaluated using the corresponding linear contrasts. *p ≤ 0.05