Table 1.
Demographic features of patients with ALS and healthy controls.
| Parameters | Affected leg (A, n = 35) | Unaffected leg (B, n = 25) | HCs (C, n = 25) | P-value | ||
|---|---|---|---|---|---|---|
| A vs. C | B vs. C | A vs. B | ||||
| Age (year) | 52.94 ± 8.66 (35–70) | 54.19 ± 10.57 (30–78) | 49.32 ± 9.31 (33–68) | >0.05 | >0.05 | >0.05 |
| Gender (male:female) | 17:15 | 18:12 | 15:10 | >0.05 | >0.05 | >0.05 |
| Height (cm) | 164.89 ± 7.12 | 166.52 ± 8.79 | 168.72 ± 6.66 | >0.05 | >0.05 | >0.05 |
| Disease duration (months) | 12.5(9) (3–48) | 12(7) (5–29) | NA | NA | NA | 0.570 |
| Disease onset (bulbar:upper limbs:lower limbs) | 6:17:12 | 8:17:0 | NA | NA | NA | 0.005 |
| Total MRC scores | 79.78 ± 11.38 (48–98) | 83.8 ± 8.23 (58–100) | NA | NA | NA | 0.064 |
| ALSFRS-R | 38.66 ± 6.01 (26–48) | 41.44 ± 2.97 (36–47) | NA | NA | NA | 0.096 |
| UMN scores | 40.80 ± 13.58 (20–64) | 37.70 ± 13.86 (4–64) | NA | NA | NA | 0.381 |
ALS, amyotrophic lateral sclerosis; HCs, healthy controls; MRC, Medical Research Council; ALSFRS-R, amyotrophic lateral sclerosis functional rating scale-revised; UMN, upper motor neuron; NA, not applicable. Values with significant differences printed in bold characters.