Table 1.
HCM Patients (n = 50) | Healthy Control Subjects (n = 30) | p Value | |
---|---|---|---|
Age, yrs | 47 ± 14 | 46 ± 16 | 0.70 |
Male | 37 (74) | 21 (70) | 0.70 |
Heart rate, beats/min | 57 ± 10 | 58 ± 11 | 0.75 |
LV end-diastolic volume, ml | 154 ± 32 | 157 ± 37 | 0.78 |
LV ejection fraction, % | 76 ± 5 | 68 ± 5 | <0.0001 |
LV mass index, g/m2 | 74 ± 23 | 54 ± 12 | <0.0001 |
Left atrial diameter, mm | 39 ± 7 | 32 ± 6 | <0.0001 |
Maximum LV wall thickness, mm | 21 ± 4 | 11 ± 1 | <0.0001 |
ECV | 0.32 ± 0.04 | 0.28 ± 0.03 | 0.001 |
LGE present | 22 (44) | 0 (0) | — |
LGE, % LV mass | 5 ± 7 | 0 | — |
Values are mean ± SD or n (%). Bold p values are significant.
ECV = extracellular volume; HCM = hypertrophic cardiomyopathy; LGE = late gadolinium enhancement; LV = left ventricular.