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. 2019 May 29;10:631. doi: 10.3389/fphys.2019.00631

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Copyright © 2019 Yang, Luo, Long, Du, Xu, Zhao, Du, Luo, Wang and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of different baits on expression level of miRNAs related to oxidative stress in liver of common carp via miRNA-seq and qRT-PCR. (A) Five antioxidant-related miRNAs validated using miRNA-seq. * is considered to indicate differential expression of miRNA between groups A and M or groups P and M. (B) Five antioxidant-related miRNAs validated using qRT-PCR. ^a,b,cNot sharing a common superscript letter was significantly different (p < 0.05) as determined by Duncan’s multiple range test. Values are means ± SD, n = 6. MiR-137-3p, miR-143-3p, miR-146a-5p, miR-21-5p, and miR-125b-5p were reported to be related to oxidative stress, and the expression level of five known microRNAs via miRNA-seq had highly similar trend with the relative expression level of five known microRNAs via qRT-PCR.