Fig 1.

Biophysical properties of T-type calcium currents (T-currents) in the juvenile rat subiculum. (a) Average T-current I-V traces from representative subicular neurones for V_t from −75 to −40 mV (the peak of activation) from V_h of −90 mV in 5 mV increments (top), and traces generated using a double-pulse protocol with 3.6-s prepulses to variable voltages (from −110 to −70 mV in 5 mV increments) and test potential of −50 mV (bottom); not all data points are displayed. (b) Average current amplitudes of the voltage dependence for activation and steady-state inactivation. (c) The voltage dependence of activation (G/G_max) and steady-state inactivation (I/I_max) is shown with V₅₀ values noted in the parentheses. Note the ‘window’ current depicted by the grey area below the intersection of the curves. Results are expressed as mean (standard error of mean).