Table V.
Expression of COL5A1 in breast cancer and its association with clinicopathological features.
| COL5A1 | |||||
|---|---|---|---|---|---|
| Clinicopathological variables | Cases | Low expression | High expression | χ2 | P-value |
| Age (years) | 0.138 | 0.710 | |||
| ≤50 | 90 | 8 | 82 | ||
| >50 | 46 | 5 | 41 | ||
| Histological grade (8) | 0.248 | 0.619 | |||
| I+II | 97 | 8 | 89 | ||
| III | 39 | 5 | 34 | ||
| Tumor size (cm) | 0.946 | 0.623 | |||
| ≤2 | 33 | 4 | 29 | ||
| 2-5 | 80 | 8 | 72 | ||
| >5 | 23 | 2 | 21 | ||
| Lymph node metastasis (8) | 0.013 | 0.911 | |||
| No (N0) | 49 | 5 | 44 | ||
| Yes (N1-N3) | 87 | 8 | 79 | ||
| Distant metastasis (8) | 0.693 | 0.405 | |||
| M0 | 129 | 11 | 118 | ||
| M1 | 7 | 2 | 5 | ||
| Clinical stage (8) | 0.142 | 0.707 | |||
| I+II | 85 | 7 | 78 | ||
| III+IV | 51 | 6 | 45 | ||
| Molecular type (8) (128 cases) | 0.748 | 0.862 | |||
| Luminal A | 16 | 1 | 15 | ||
| Luminal B | 77 | 8 | 70 | ||
| HER-2 (overexpression) | 16 | 2 | 14 | ||
| Triple negative type | 18 | 1 | 17 | ||
COL5A1, collagen type V α-1 chain; N, node; M, metastasis.