Table 5. The interaction analysis of FGFR2 polymorphisms and drinking status in osteoporosis risk.
Genotype | Drinking | Case, n=145 | Control, n=123 | P-value | OR (95% CI) | |
---|---|---|---|---|---|---|
rs2981582 | CC | No | 36 | 47 | ||
CC | Yes | 15 | 11 | 0.202 | 1.780 (0.730–4.339) | |
CT+TT | No | 61 | 49 | 0.097 | 1.625 (0.915–2.886) | |
CT+TT | Yes | 33 | 16 | 0.008 | 2.693 (1.287–5.634) | |
rs2420946 | GG | No | 23 | 35 | ||
GG | Yes | 13 | 10 | 0.168 | 1.978 (0.744–5.260) | |
AG+AA | No | 74 | 61 | 0.053 | 1.846 (0.987–3.452) | |
AG+AA | Yes | 35 | 17 | 0.004 | 3.133 (1.432–6.852) | |
rs1219648 | TT | No | 21 | 31 | ||
TT | Yes | 11 | 11 | 0.445 | 1.476 (0.542–4.023) | |
CT+CC | No | 76 | 65 | 0.096 | 1.726 (0.905–3.291) | |
CT+CC | Yes | 37 | 16 | 0.002 | 3.414 (1.524–7.648) | |
rs2981579 | CC | No | 14 | 29 | ||
CC | Yes | 13 | 6 | 0.009 | 4.488 (1.409–14.298) | |
CT+TT | No | 83 | 67 | 0.008 | 2.566 (1.256–5.243) | |
CT+TT | Yes | 35 | 21 | 0.003 | 3.452 (1.496–7.968) |