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. 2019 Jun 5;9:8299. doi: 10.1038/s41598-019-44575-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Summary of differential gene expression by MC3T3-E1 sub clones and primary calvarial osteoblasts cultured in differentiation media. (A) Up-regulated or (B) down-regulated transcripts that were >2-fold and p < 0.05 between control and differentiation media by are shown. Fold-difference data for all 84 genes assayed can be found in Supplementary Table S2. Results of unsupervised hierarchical cluster analysis can be found in Supplementary Fig. S2.