Table 3.
cell proliferation of fibroblasts and osteoblasts using the Real-time cell analysis assay.
| RTCA - Fibroblasts | 24 h | 48 h | 72 h |
|---|---|---|---|
| PC | 6.03 (CI: 5.91–6.14) | 5.77 (CI: 5.32–6.21) | 5.83 (CI: 5.20–6.49) |
| NC | 1.89 (CI: 1.55–2.24) | 1.54 (CI: 1.16–1.94) | 1.25 (CI: 0.96–1.63) |
| PRP | 0.63 (CI: 0.51–0.73) | 0.43 (CI: 0.12–0.72) | 0.34 (CI: 0.00–0.67) |
| PRF | 3.66 (CI: 2.21–4.72) | 3.95 (CI: 3.80–4.17) | 4.86 (CI: 4.56–5.07) |
| ZA | 0.95 (CI: 0.83–1.04) | 0.53 (CI: 0.45–0.63) | 0.0 ± 0.0 |
| ZA + PRP | 0.42 (CI: 0.32–0.57) | 0.23 (CI: 0.14–0.34) | 0.09 (CI: 0.03–0.15) |
| ZA + PRF | 1.86 (CI: 1.08–2.67) | 0.96 (CI: 0.39–1.73) | 0.42 (CI: 0.06–0.88) |
| RTCA - Osteoblasts | 24 h | 48 h | 72 h |
| PC | 0.69 (CI: 0.47–0.86) | 0.87 (CI: 0.68–1.00) | 0.98 (CI: 0.80–1.13) |
| NC | 0.92 (CI: 0.59–1.14) | 0.23 (CI: 0.19–0.29) | 0.24 (CI: 0.00–1.06) |
| PRP | 0.49 (CI: 0.42–0.56) | 0.09 (CI: 0.01–0.16) | 0.15 (CI: 0.00–0.42) |
| PRF | 0.86 (CI: 0.17–1.75) | 1.01 (CI: 0.34–2.03) | 1.20 (CI: 0.23–2.62) |
| ZA | 0.47 (CI: 0.29–0.75) | 0.0 ± 0.0 | 0.0 ± 0.0 |
| ZA + PRP | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| ZA + PRF | 0.06 (CI: 0.0–0.28) | 0.0 ± 0.0 | 0.0 ± 0.0 |
(PC = positive control; NC = negative control, PRP = platelet rich plasma; PRF = platelet rich fibrin, ZA = zoledronic acid); CI = confindence interval of 95%; values are medians of the cell index measured by RTCA.