Skip to main content
. 2019 Jun 5;10(6):441. doi: 10.1038/s41419-019-1631-0

Fig. 1. Effect of chronic cerebral ischemia (CCI) to neuronal apoptosis and relative expression levels of Snhg8, miR-384, and Hoxa13.

Fig. 1

a H&E-stained (upper part, ×100 or ×400, scale bar = 100 or 25 μm) and terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end labeling (TUNEL) assay (lower part, ×200, scale bar = 50 μm) sections of the hippocampus CA1 region of Sham and CCI group (n = 4, each group). Data are represented as mean ± SD, *P < 0.05 vs. Sham group. b Quantitative real-time PCR and western blot (WB) were used to detect the relative expression levels of Snhg8 (upper left part, n = 5, each group), miR-384 (upper right part, n = 5, each group), and Hoxa13 (lower right part, n = 5, each group). Data are represented as mean ± SD, *P < 0.05 vs. Sham group. c Flow cytometry analysis of CCI-induced HT22 cells (n = 5, each group). Data are represented as mean ± SD, **P < 0.01 vs. Control group. d The expression levels of Snhg8 RNA (upper left part, n = 5, each group), miR-384 RNA (upper right part, n = 6, each group), and Hoxa13 protein (lower part, n = 5, each group) in CCI-induced HT22 cells. Data are represented as mean ± SD, *P < 0.05 vs. Control group, **P < 0.01 vs. Control group