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. 2019 Jun 5;10(6):441. doi: 10.1038/s41419-019-1631-0

Fig. 2. Snhg8 protected chronic cerebral ischemia (CCI)-induced neuronal apoptosis, while miR-384 exacerbated CCI-induced neuronal apoptosis.

Fig. 2

a Flow cytometry analysis of CCI-induced HT22 cells with overexpression of Snhg8 (n = 5, each group). Data are represented as mean ± SD, *P < 0.05 vs. Pre-NC group. b Expression analysis of miR-384 RNA (left part, n = 5, each group), Hoxa13 protein (middle part, n = 5, each group), and FAM3A protein (right part, n = 5, each group) in CCI-induced HT22 cells. Data are represented as mean ± SD, *P < 0.05 vs. Pre-NC group, **P < 0.01 vs. Pre-NC group. c Flow cytometry analysis of CCI-induced HT22 cells with transfection of miR-384 (n = 4, each group). Data are represented as mean ± SD, *P < 0.05 vs. Pre-NC group, ##P < 0.01 vs. anti-NC group. d Expression analysis of Snhg8 RNA (left part, n = 5, each group), Hoxa13 protein (middle part, n = 4, each group) and FAM3A protein (right part, n = 6, each group) in CCI-induced HT22 cells with transfection of miR-384. Data are represented as mean ± SD, *P < 0.05 vs. Pre-NC group, #P < 0.05 vs. anti-NC group, ##P < 0.01 vs. anti-NC group