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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Genes Chromosomes Cancer. 2019 Mar 15;58(7):484–499. doi: 10.1002/gcc.22731

Figure 3. Mitotic bookmarking maintains nuclear organization, cellular identity and genome regulation in daughter cells.

Figure 3.

Bookmarking is the retention of transcription factors and epigenetic modifications on mitotic chromosomes. Genes that are bookmarked (green) are active in early G1 compared with genes that are not bookmarked during mitosis (red). Bookmarking of the nucleolar organizer regions (NORs) is key to the biogenesis of nucleoli upon exit from mitosis.