Table 2.
Entire cohort: univariate and multivariate analysis of factors influencing overall survival (n = 454)
| Univariate | Multivariate | ||
|---|---|---|---|
| P | Hazard ratio | P | |
| Underweight (BMI < 18.5 kg/m2) | .37 | – | |
| Performance status (0–1 versus 2–3) | < .01 | 1.6 (1.21–2.11) | < .01 |
| Weight loss at diagnosis | < .01 | – | |
| Continuous weight loss at restaging | .01 | 9.56 (6.32–14.5) | < .01 |
| Jaundice | .28 | – | |
| Pain | .12 | – | |
| CA 19-9 level | .08 | – | |
| Tumor location (head versus body/tail) | .54 | – | |
| Tumor staging (BRPC versus LAPC) | < .01 | – | |
| Resection | < .01 | .38 (.284–.513) | < .01 |
Entries in italic are significant, even if only in univariate analysis
BMI body mass index, CA 19-9 carbohydrate antigene 19-9, BRPC borderline resectable pancreatic cancer, LAPC locally advanced pancreatic cancer