Table 4.
Resected patients: univariate and multivariate analysis of factors influencing overall survival (n = 142)
| Univariate | Multivariate | ||
|---|---|---|---|
| P | Hazard ratio | P | |
| Underweight (BMI < 18.5 kg/m2) | .44 | – | |
| Obesity (BMI ≥ 30 kg/m2) | .01 | 2.99 (1.34–6.66) | <.01 |
| Performance status (1 versus 0) | < .01 | 1.91 (1.15, 3.17) | .01 |
| Weight loss at diagnosis | .14 | – | |
| Continuous weight loss at restaging | .91 | – | |
| Jaundice | .87 | – | |
| Abdominal pain | .68 | – | |
| CA 19-9 level | .34 | – | |
| Tumor location (head versus body/tail) | .86 | – | |
| Tumor staging (BL versus LA) | < .01 | – | |
| R1 status | 1.75 (1.03–2.96) | .04 | |
| Lymph node invasion | 1.66 (1.01–2.74) | .04 | |
| Adjuvant treatment | < .01 | .5 (.299–.843) | < .01 |
Entries in italic are significant, even if only in univariate analysis
BMI body mass index, CA 19-9 carbohydrate antigene 19-9, BL borderline, LA locally advanced