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. 2019 Jun 5;18:132. doi: 10.1186/s12944-019-1045-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — LCAT mutations found in a Chilean patient with hypoalphalipoproteinemia and her relatives. (a) Each family member is shown with his/her genotype in for p.V333 M and p.M404 V mutations. Proband is indicated by a black arrow. (b) The chart shows FPLC fractions for HDL, LDL and VLDL lipoproteins in the proband, indicating near-absence of HDL-lipoproteins and very low levels of LDL-lipoproteins