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. 2019 Jun 5;17:106. doi: 10.1186/s12916-019-1341-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The relationship between ICPI and local immune status. a The network of immune features in HCC tissues. b Correlation between ICPI and the density of intratumoral CD4⁺, CD20⁺, CD45RO⁺, and CD45RA⁺ cells. c Immunostaining of intratumoral CD4⁺, CD20⁺, CD45RO⁺, CD45RA⁺, and CD68 cells across 3 subgroups. Bar, 20 μm