Table 1.
Current clinical trials of visual prosthesis devices
| Type | Clinical trial | Title/Sponsor | Status | Disease | Device | Last update |
|---|---|---|---|---|---|---|
| Epiretinal | NCT00407602 |
Argus II Retinal Stimulation System Feasibility Protocol Second Sight Medical Products |
A | RP | Argus II | 2015-05-29 |
| NCT01490827 |
Argus II Retinal Prosthesis System Post-Market Surveillance Study Second Sight Medical Products |
R |
oRD RP |
Argus II | 2017-10-09 | |
| NCT01860092 |
New Enrollment Post-Approval Study of the Argus II Retinal Prosthesis Second Sight Medical Products |
R | RP | Argus II | 2018-07-23 | |
| NCT01999049 |
Observational Study of the Argus II Retinal Prosthesis System University Health Network, Toronto |
U | RP | Argus II | 2015-04-24 | |
| NCT02227498 |
Argus II Retinal Prosthesis System Dry AMD Feasibility Study Protocol Second Sight Medical Products |
A | AMD | Argus II | 2017-10-09 | |
| NCT02303288 |
Post-Market Study of the Argus II Retinal Prosthesis System – France Second Sight Medical Products |
A |
RP C |
Argus II | 2018-07-20 | |
| NCT03248388 |
Argus II/ORCAM Device Study Mayo Clinic, Second Sight Medical Products, Orcam Technologies Ltd. |
R | RP |
Argus II ORCAM |
2018-11-12 | |
| NCT03418116 |
Argus II Retinal Prosthesis System -- Better Vision RP Study Second Sight Medical Products |
R |
RP C |
Argus II | 2017-09-05 | |
| NCT03510234 |
Self-confidence Study in Patients With Argus II Artificial Retina University Hospital, Strasbourg |
R | RP | Argus II | 2018-07-06 | |
| NCT03635645 |
Experimental and Clinical Studies of Retinal Stimulation University of Michigan |
R | RP | Argus II | 2018-08-17 | |
| Subretinal | NCT02670980 |
Compensation for Blindness With the Intelligent Retinal Implant System (IRIS 2) in Patients With Retinal Dystrophy Pixium Vision SA |
A |
RP CRD C |
IRIS 2 | 2017-01-24 |
| NCT03333954 |
Feasibility Study of Compensation for Blindness with the PRIMA System in Patients With Dry Age Related Macular Degeneration Pixium Vision SA |
A | dAMD | PRIMA | 2018-07-12 | |
| NCT03392324 |
PRIMA Feasibility Study in Atrophic Dry AMD Pixium Vision SA |
R | dAMD | PRIMA | 2018-05-01 | |
| NCT03561922 |
Impact on Daily Life of Patients Using the Subretinal Implant Alpha AMS Retina Implant AG |
R | RD | Alpha AMS | 2018-10-26 | |
| NCT03629899 |
Retina Implant Alpha AMS in Blind Patients With Retinitis Pigmentosa Wills Eye/Retina Implant AG |
R | RP | Alpha AMS | 2019-01-09 | |
| Choroidal | NCT03406416 |
Study of a Suprachoroidal Retinal Prosthesis Mobius Medical Pty Ltd., Bionic Vision Technologies, and four others |
E |
RP C |
Bionic Eye | 2018-03-22 |
| Cortical | NCT02747589 |
Feasibility of Stimulating the Visual Cortex in Blind University of California, Los Angeles |
A | Ba | NeuroPace | 2018-02-12 |
| NCT02983370 |
Development of a Cortical Visual Neuroprosthesis for the Blind Universidad Miguel Hernandez de Elche, Hospital IMED Elche |
R | B | CORTIVIS | 2017-10-27 | |
| NCT03344848 |
Early Feasibility Study of the Orion Visual Cortical Prosthesis System Second Sight Medical Products |
R | Ba | Orion | 2018-07-16 |