Table 2.
Association between baseline patient characteristics and mortality according to Cox regression analysis, unadjusted and adjusted for potential confounders
| Unadjusted Cox regression model | Adjusted Cox regression model | |||||
|---|---|---|---|---|---|---|
| Crude HR | CI 95% | p value | Adjusted HR | CI 95% | p value | |
| Age (ref: 65–74 yrs) | ||||||
| 75–84 yrs | 1.13 | 0.69–1.84 | 0.633 | 0.88 | 0.53–1.45 | 0.621 |
| 85–94 yrs | 2.27 | 1.43–3.61 | 0.001 | 1.48 | 0.92–2.39 | 0.107 |
| ≥ 95 yrs | 4.33 | 2.47–7.57 | < 0.001 | 2.96 | 1.65–5.31 | < 0.001 |
| Gender (ref: male) | ||||||
| Female | 0.63 | 0.50–0.80 | < 0.001 | 0.71 | 0.55–0.90 | 0.005 |
| Therapy (ref: control group) | ||||||
| Warfarin | 2.15 | 1.59–2.92 | < 0.001 | 1.42 | 1.03–1.95 | 0.034 |
| Antiplatelet | 1.23 | 0.96–1.58 | 0.10 | 0.95 | 0.73–1.23 | 0.687 |
| ASA score (ref: 1/2) | ||||||
| 3 | 3.27 | 1.20–8.91 | 0.021 | 1.72 | 0.62–4.79 | 0.300 |
| 4/5 | 7.79 | 2.90–20.96 | < 0.001 | 2.46 | 0.87–6.92 | 0.089 |
| CCI | 1.32 | 1.26–1.39 | < 0.001 | 1.24 | 1.17–1.32 | < 0.001 |
| Time to surgery (ref: < 48 h) | ||||||
| > 48 h | 1.24 | 0.99–1.56 | 0.066 | 1.53 | 1.04–2.25 | 0.032 |
| Blood loss (ref: 0–490 ml) | ||||||
| 491–980 ml | 1.92 | 1.38–2.66 | < 0.001 | 1.60 | 1.14–2.23 | 0.006 |
| 981–1470 ml | 1.97 | 1.36–2.88 | < 0.001 | 1.38 | 0.94–2.04 | 0.097 |
| > 147 ml | 2.60 | 1.88–3.59 | < 0.001 | 1.81 | 1.30–2.53 | < 0.001 |
| AO/OTA Classification (ref: lateral fracture—A) | ||||||
| Medial fracture—B | 0.89 | 0.71–1.12 | 0.332 | |||
| Types of surgical Procedure (ref: fixation) | ||||||
| Reconstruction | 0.93 | 0.74–1.17 | 0.515 | |||