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. 2019 May 31;13:1889–1900. doi: 10.2147/DDDT.S194787

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© 2019 Wang et al.

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SA-A inhibits HSCs activation to prevent liver fibrosis. (A) Effects of SA-A on the expression of a-SMA in the liver tissues were measured by western blot analysis. (B) Immunohistochemistry staining of a-SMA in the liver tissues, magnification: ×100. (C) Relative mRNA levels of α-SMA, PDGF-βR, CTGF, Desmin, Vimentin, and TGF-β1. Data are expressed as the mean ± S.D.. ^aP<0.05 as compared with control (C) group, ^bP<0.05 as compared with model (M) group, ^cP<0.05 as compared with SA-A 5 mg/kg (L) group.

Abbreviations: HSCs, hepatic stellate cells; SA-A, salvianolic acid A.