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. 2019 Jun 5;2019(6):CD009670. doi: 10.1002/14651858.CD009670.pub4

1. Summary of control and intervention characteristics.

  Intervention Control  
Study ID Pharmacotherapy Modality
(included face‐to‐face/
telephone only)
Number of contacts Total duration (minutes) Number of contacts Total duration (minutes) Comments
Ahluwalia 2006 NRT Face‐to‐face 6 120 6 120  
Aimer 2017 NRT Face‐to‐face 4 Unclear Unclear Unclear  
Alterman 2001 NRT Face‐to‐face 16 4290 1 30 Multiple arms ‐ highest vs lowest intensity
Aveyard 2007 NRT Face‐to‐face 7 140 4 80  
Bailey 2013 NRT Face‐to‐face 19 950 10 500  
Baker 2015 NRT Face‐to‐face 17 1050 17 290  
Bastian 2012 NRT Telephone 5 100 5 100  
Begh 2015 NRT Face‐to‐face 7 112 7 112  
Berndt 2014 NRT Face‐to‐face 7 285 7 105  
Bloom 2017 NRT Face‐to‐face 20 400 20 880 Exercise sessions/time excluded
Bock 2014 NRT Face‐to‐face 3 Unclear 1 Unclear  
Boyle 2007 Choice Face‐to‐face 9 Unclear 0 0  
Bricker 2014 NRT Telephone 5 90 5 90  
Brody 2017 NRT & Bupropion Face‐to‐face 22 970 12 720  
Brown 2013 NRT Face‐to‐face Unclear Unclear Unclear Unclear  
Busch 2017 NRT Face‐to‐face 6 220 6 87.5  
Bushnell 1997 NRT Face‐to‐face 8 480 4 240  
Calabro 2012 NRT Face‐to‐face 2 120 1 5 Intervention also had "access to 5 web‐based booster sessions"
Cook 2016 NRT Face‐to‐face 11 130 0 0 Multifactorial ‐ highest vs lowest intensity
Cropsey 2015 NRT Face‐to‐face 4 100 1 Unclear  
Ellerbeck 2009 Choice Face‐to‐face 6 Unclear 0 0 Multiple arms ‐ highest vs lowest intensity
Ferguson 2012 NRT Telephone 6 Unclear Unclear Unclear  
Fiore 2004 NRT Face‐to‐face 5 Unclear 0 0 Multiple arms ‐ highest vs lowest intensity
Gariti 2009 Choice Face‐to‐face 10 125 4 30  
Gifford 2011 Bupropion Face‐to‐face 20 Unclear 1 60  
Ginsberg 1992 NRT Face‐to‐face 5 Unclear 2 Unclear  
Hall 1985 NRT Face‐to‐face 14 1050 4 Unclear  
Hall 1987 NRT Face‐to‐face 14 1050 5 300  
Hall 1994 NRT Face‐to‐face 10 1200 5 450  
Hall 1998 Nortriptyline Face‐to‐face 10 1200 5 450  
Hall 2002 Bupropion/Nortriptyline Face‐to‐face 5 450 4 30  
Hall 2009 NRT & Bupropion Face‐to‐face 11 330 5 Unclear Multifactorial study design
Hasan 2014 NRT Face‐to‐face 7 195 6 105  
Hollis 2007 NRT Telephone 4 100 1 15 Multiple arms ‐ highest vs lowest intensity
Huber 2003 NRT Face‐to‐face 5 450 5 225  
Humfleet 2013 NRT Face‐to‐face 6 300 1 'Brief' Multiple arms ‐ highest vs lowest intensity
Jorenby 1995 NRT Face‐to‐face 8 480 0 0 Multiple arms ‐ highest vs lowest intensity
Kahler 2015 NRT Face‐to‐face 6 210 6 210  
Killen 2008 NRT & Bupropion Face‐to‐face 10 300 10 200  
Kim 2015 NRT Face‐to‐face 8 320 8 80  
LaChance 2015 NRT Face‐to‐face 7 420 7 420  
Lando 1997 NRT Face‐to‐face 4 48 0 0 Multiple arms ‐ highest vs lowest intensity
Lifrak 1997 NRT Face‐to‐face 20 736.5 4 82.5  
Lloyd‐Richardson 2009 NRT Face‐to‐face 5 Unclear 2 Unclear  
MacLeod 2003 NRT Telephone 5 60 0 0  
Macpherson 2010a NRT Face‐to‐face 8 480 8 480  
Matthews 2018 NRT Face‐to‐face 6 540 6 540  
McCarthy 2008 Bupropion Face‐to‐face 13 Unclear 13 Unclear Control received 80 minutes less contact than intervention
NCT00879177 NRT & Varenicline Face‐to‐face 9 Unclear 5 Unclear  
Ockene 1991 NRT Face‐to‐face 5 45 2 15  
O'Cleirigh 2018 NRT Face‐to‐face 10 600 5 100  
Okuyemi 2013 NRT Face‐to‐face 6 105 1 12.5  
Otero 2006 NRT Face‐to‐face 4 240 1 20 Multiple arms ‐ highest vs lowest intensity
Patten 2017 NRT Face‐to‐face 36 1080 36 1080 Intervention group: "exercise counselling delivered while the participant was engaged in exercise" ‐ have left this time in as also counselling
Prapavessis 2016 NRT Face‐to‐face 64 1985 59 1860 Multiple arms ‐ highest vs lowest intensity
Reid 1999 NRT Face‐to‐face 6 Unclear 3 45  
Rohsenow 2014 NRT Face‐to‐face 3 65 3 35  
Rovina 2009 Bupropion Face‐to‐face 9 540 1 15 Multiple arms ‐ highest vs lowest intensity
Schlam 2016 NRT Face‐to‐face 12 320 4 200 Multifactorial study design
Schmitz 2007a Bupropion Face‐to‐face 7 420 7 420  
Simon 2003 NRT Face‐to‐face 6 195 1 10  
Smith 2001 NRT Face‐to‐face 6 90 0 0 Multiple arms ‐ highest vs lowest intensity
Smith 2013a NRT Telephone 4 67 4 60 Exact duration of contact not recorded, but averages given, intervention: 67.0 (± 25.8), control: 60.1 (± 23.9)
Smith 2014 Varenicline Face‐to‐face 5 Unclear 5 Unclear Comparing culturally‐tailored with standard counselling ‐ duration of sessions not stated
Solomon 2000 NRT Telephone See note See note 0 0 Control = "access to quitline"; intervention = "up to 12 calls" ‐ averaged 7 calls at 9 minutes each
Solomon 2005 NRT Telephone 8.2 80 0 0 Intervention numbers based on average number/duration of calls
Stanton 2015 NRT Face‐to‐face 7 Unclear 3 Unclear  
Stein 2006 NRT Face‐to‐face 3 65 2 5 Control offered "up to 2 visits", intervention only offered 3rd visit if ready to quit
Strong 2009 Bupropion Face‐to‐face 12 1440 12 1440  
Swan 2003 Bupropion Telephone 4 Unclear 1 7.5 Multiple arms ‐ highest vs lowest intensity
Swan 2010 Varenicline Telephone 5 67 0 0  
Tonnesen 2006 NRT Face‐to‐face 12 270 10 150  
Van Rossem 2017 Varenicline Face‐to‐face 10 120 1 20 Duration of sessions not stipulated, but maximum amounts recorded in paper. Intervention: 120, control: 20
Vander Weg 2016 Choice Telephone 6 150 0 0 Intervention sessions listed as 20 to 30 minutes ‐ control was referral to a quitline, but there were no mandated sessions, so contact listed as 0
Vidrine 2016 (CBT) NRT Face‐to‐face 8 960 4 40 Vidrine study intervention 2 (control split)
Vidrine 2016 (MBAT) NRT Face‐to‐face 8 960 4 40 Vidrine study intervention 1 (control split)
Wagner 2016 NRT Face‐to‐face 12 Unclear 12 Unclear Sessions' duration not reported
Warner 2016 NRT Face‐to‐face 1 5 1 5  
Webb Hooper 2017 NRT Face‐to‐face 9 945 9 945 Exact duration not listed, but approximate range given
Wewers 2017 NRT Face‐to‐face 7 210 6 180 Compared 2 interventions, less intensive counted as control
Wiggers 2006 NRT Face‐to‐face 3 Unclear 1 Unclear  
Williams 2010 NRT Face‐to‐face 24 1080 9 180  
Wu 2009 NRT Face‐to‐face 4 240 4 240  
Yalcin 2014 Choice Face‐to‐face 14 730 9 150