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. 2019 Jun 5;2019(6):CD009670. doi: 10.1002/14651858.CD009670.pub4

Aimer 2017.

Methods Setting: rheumatology clinic (single centre), Christchurch, New Zealand
Recruitment: smokers with rheumatoid arthritis. No mention of intended selection for motivation but the authors mentioned that the study population was likely to have been highly motivated
Participants 39 smokers; 55% female; average age 56.5; average cigarettes per day 16.5
Therapists: community‐based arthritis educators trained in smoking cessation
Interventions Pharmacotherapy: NRT for 8 weeks
1. usual care (brief advice and subsidised NRT) for 3 months
2. usual care + rheumatoid arthritis‐specific programme for 3 months via face‐to‐face, telephone and email; 4 sessions at week 0, 1, 4, 8
Outcomes Continuous abstinence at 3 and 6 months
Validation: none
Source of Funding/CoI New Zealand Health Research Council, Arthritis New Zealand and University of Otago Research Fund. Authors declared receipt of consultant fees, speaking fees, and/or honoraria from AbbVie and Janssen (less than $10,000 each).
Notes New for 2019 update
One participant was excluded from analysis after intervention and follow‐up when found not to have rheumatoid arthritis. Did not contribute to analysis 1.2 or analysis 1.3 as duration of control group contact not specified
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random sequence generated by a biostatistician using an Excel spreadsheet in 6 blocks x 8 allocations
Allocation concealment (selection bias) Unclear risk Insufficient details given
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Self‐report only
Incomplete outcome data (attrition bias) 
 All outcomes Low risk 0‐15.8% lost to follow‐up at 6 months