Hall 1985.
Methods | Setting: clinic, USA Recruitment: referred by physicians, friends or self | |
Participants | 84 smokers in relevant arms; 53% M, av age 38, av cpd 30.5 Therapists: 2 psychologists | |
Interventions | Pharmacotherapy: NRT; gum (2 mg, available for 6 months) 1. Intensive behavioural treatment (incl relapse prevention skill training, relaxation, 30 seconds aversive smoking of 3 cigs). 14 x 75 min sessions over 8 weeks 2. Low‐contact . Met x 4 in 3 weeks, educational materials, written exercises, group discussion 3. Intensive behavioural, no gum. Not included in this review |
|
Outcomes | Abstinence at 52 weeks (assume PP) Validation: CO < 10 ppm, thiocyanate < 85 mg/mL, reports of significant others (biochemical measures failed to confirm self‐report in 3 instances) | |
Source of Funding/CoI | National Institute on Drug Abuse. No declarations of interest | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "Randomly assigned within time constraints." Author clarification: "There were two or more treatment conditions available within any time block, and participants were randomly assigned to conditions within that time block". |
Allocation concealment (selection bias) | Unclear risk | No details given |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Biochemically validated |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 3 dropouts from group 2 and 3 from group 3. Assumed to be included in denominator for reported % abstinent used to derive numbers quit |