Hall 1994.
Methods | Country: USA Recruitment: community volunteers or referrals | |
Participants | 149 smokers (> 10 cpd) 52% F, av age 41, av cpd 25, 31% had history of MDD Therapists: physician, psychologist. Both received training. | |
Interventions | Pharmacotherapy: NRT (gum, 2 mg for up to 12 wks, tapering from wk 4)
1. Mood Management. 10 x 2 hr sessions over 8 wks. Similar to control, plus specific cognitive‐behavioural components for developing skills for coping with situations leading to poor mood. Thought stopping, rational‐emotive techniques, relaxation etc. 2. Standard group therapy. 5 x 90 min sessions over 8 wks. Information and group support for planning and implementing individual strategies |
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Outcomes | Continuous abstinence at 52 wks (confirmed quit at all prior assessments and no smoking in previous wk) Validation: CO ≤ 10 ppm and urine cotinine ≤ 60 ng/mL | |
Source of Funding/CoI | National Institute on Drug Abuse. Merrell Dow Pharmaceuticals Inc. provided drugs. No declarations of interest. | |
Notes | Both behavioural interventions were relatively intensive. Positive effect reported for subgroup with history of major depression | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Randomised, method not described |
Allocation concealment (selection bias) | Unclear risk | No details given |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Biochemically validated |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Dropouts included as smokers, but numbers not specified |