| Methods |
Setting: substance abuse outpatient facility, USA
Recruitment: community volunteers |
| Participants |
69 smokers; 61% F, av age 39, av cpd 25 |
| Interventions |
Pharmacotherapy: nicotine patch (24‐hr, 10‐wk tapered dose)
1. Moderate intensity ‐ 4 meetings with nurse practitioner who reviewed S‐H materials and instructed in patch use
2. High intensity. As 1 plus 16 weekly 45‐min cognitive behavioural relapse prevention therapy from clinical social worker or psychiatrist experienced in addiction treatment |
| Outcomes |
Abstinence at 12 months, 1‐week PP
Validation: urine cotinine for some participants, but no corrections made for misreporting |
| Source of Funding/CoI |
None stated |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
Block randomisation (block size 10) |
| Allocation concealment (selection bias) |
Unclear risk |
No details given |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Biochemically validated |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Low rate of attrition (though breakdown by group not provided): 12 administrative dropouts/exclusions not included in analyses |
