Rohsenow 2014.

Methods	Setting: residential substance abuse treatment programme, USA Recruitment: research therapist assessed patients for eligibility
Participants	165 alcoholic smokers (≥ 10 cpd for 6 m), 60% M, av age 34, av cpd 21 Therapists: research therapists
Interventions	Pharmacotherapy: NRT; patch preferred, mostly used for 2‐3 months 1. Brief advice ˜15 mins, assessed smoking rate and interest in quitting, ± 2 x 5 to 15‐min boosters at 7 & 30 days 2. Motivational interviewing, 45 min, ± 2 x 5 to 15‐min boosters at 7 & 30 days
Outcomes	Abstinence at 12 months (7‐day PP) Validation: CO < 10 ppm
Source of Funding/CoI	National Institute of Alcohol Abuse and Alcoholism, United States Department of Veterans Affairs. No declarations of interest
Notes	Booster and no‐booster conditions combined in analyses. Only 51% used NRT during the first month, 34% during the subsequent 2 months
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random numbers table
Allocation concealment (selection bias)	Low risk	Assignment in sealed envelope opened just before the first treatment session
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Biochemically validated
Incomplete outcome data (attrition bias) All outcomes	Low risk	Overall 32% lost to follow‐up; MI 35%, (28/80 including 1 death), BA 29% (25/85 including 3 deaths)