Smith 2014.

Methods	Setting: Menominee Tribal Clinic (primary care centre), USA Recruitment: all participants were receiving health care at the Menominee Tribal Clinic and were motivated to quit smoking.
Participants	103 participants, 62.1% female, average age: 39.8 (SD 13.1), average cigs/day: 14.4 (SD 7.9) Therapists: a study coordinator who was an enrolled member of the Menominee Tribe and trained as a counsellor
Interventions	Pharmacotherapy: 12 weeks of varenicline Intervention: 5 x face‐to‐face culturally tailored counselling sessions, duration not reported Control: 5 x face‐to‐face standard counselling sessions, duration not reported
Outcomes	Abstinence: 7‐day point prevalence abstinence at weeks 1, 3, and 7, and at 3 and 6 months Validation: CO < 10 ppm
Source of Funding/CoI	Wisconsin Partnership Program, the Spirit of Eagles Community Network Program, the University of Wisconsin Carbone Cancer Center, and the University of Wisconsin Center for Tobacco Research and Intervention. No declarations of interest
Notes	New for 2019 update
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	No detail given
Allocation concealment (selection bias)	Unclear risk	No detail given
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Biochemically validated
Incomplete outcome data (attrition bias) All outcomes	High risk	Attrition rate high and differed between study arms: intervention: 47.2%; control: 66.0%