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. 2019 May 31;14:4045–4057. doi: 10.2147/IJN.S210057

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© 2019 Yin et al.

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Cellular uptake and internalization of free and formulated QUE in Caco-2 cells.

Notes: (A) Cellular uptake of free QUE, QUE-PLNs and QUE-cPLNs (in the absense of presence of sodium taurocholate) at different incubation time quantified by the intracellular QUE concentration, data expressed as mean ± SD (n=3), paired t-test, **P<0.01, significantly different comapred with each other. (B) Cellular internalization of QUE-PLNs and QUE-cPLNs characterized by intracellular fluorescence intensity.

Abbreviations: QUE, quercetin; QUE-PLNs, quercetin-loaded polymer–lipid hybrid nanoparticles.