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. 2019 May 29;10:1193. doi: 10.3389/fimmu.2019.01193

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Copyright © 2019 Lisco, Wong, Price, Ye, Niemela, Anderson, Richards, Manion, Mystakelis, Similuk, Lo, Stoddard, Rosenzweig, Vanpouille, Rupert, Maric, Perez-Diez, Parenti, Burbelo, Rao and Sereti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of the proportion of CD4, CD8, and DNT-cells in patient with ALPS-FAS and CD4 lymphopenia, matched controls subjects with ALPS-FAS and healthy subjects. ^*Comparisons with statistically significant differences. (A) Proportion of CD4, CD8, and DNT cells in patients with ALPS-FAS (circles) and healthy subjects (squares). (B) Proportion of Ki67 expressing CD4, CD8, and DNT cells in patients with ALPS-FAS (circles) and healthy subjects (squares). (C) Proportion of CD4, CD8, and DNT-cells in ALPS-FAS patients with (diamonds) or without (hexagons) CD4 lymphopenia. (D) Absolute counts of CD4, CD8, and DNT-cells in ALPS-FAS patients with (diamonds) or without (hexagons) CD4 lymphopenia.