Table 1.
Study Author, Year | Region* | Level of Evidence† | Study Quality‡ | IUD Type§ | Placement Timingǁ | Delivery Method¶ | Length of Follow-up | No. Enrolled or Randomized | No. of Women With lUDs Placed | No. of Women With IUDs Placed With Follow-up (%) |
---|---|---|---|---|---|---|---|---|---|---|
Agarwal, 201 735 | Southeast Asia | II-3 | Fair | CuT380A | Immediate | Cesarean | 3 mo | 50 | 50 | 50 (100) |
Baldwin, 201650 | North America | I | Fair | Mixed | Mixed | Mixed | 6 mo | 201 | 139 | Unknown (66#) |
Bonilla Rosales, 200516 | South America | II-2 | Fair | CuT380A | Mixed | Vaginal | 3 mo | 250 | 250 | 239 (96) |
Braniff, 201538 | Western Pacific | I | Fair | LNG-IUS | Mixed | Cesarean | 6 mo | 48 | 42 | Unknown (84#) |
Bryant, 201320 | Africa | I | Poor | CuT380A | Mixed | Vaginal | 12 wk | 49 | 28 | 28 (100) |
Celen, 201118 | Eastern Mediterranean | II-3 | Good | CuT380A | Immediate | Cesarean | 12 mo | 245 | 245 | 245 (100) |
Chen, 201019 | North America | I | Good | LNG-IUS | Mixed | Vaginal | 6 mo | 124 | 96 | 84 (88) |
Chen, 201751 | North America | II-2 | Poor | Mixed | Mixed | Mixed | 6 mo | 74 | 74 | 59 (80) |
Cohen, 20169 | North America | II-3 | Poor | Mixed | Immediate | Mixed | 12 mo | 82 | 82 | 67 (82) |
Colwill, 201836 | North America | II-2 | Fair | CuT380A | Immediate | Mixed | 6 wk | 210 | 210 | 169 (81) |
Dahlke, 201139 | North America | I | Poor | LNG-IUS | Mixed | Vaginal | 6 mo | 53 | 46 | 45 (98) |
Dias, 201521 | Southeast Asia | II-2 | Poor | CuT380A | Immediate | Mixed | 6 wk | 91 | 91 | 91 (100) |
Eggebroten, 201752 | North America | II-2 | Poor | Mixed | Immediate | Mixed | 6 mo | 211 | 211 | 186 (88) |
Elsedeek, 201241 | Eastern Mediterranean | II-3 | Fair | LNG-IUS | Immediate | Cesarean | 2y | 65 | 65 | 62 (95) |
Elsedeek, 201540 | Eastern Mediterranean | II-3 | Fair | LNG-IUS | Immediate | Cesarean | 5y | 80 | 80 | 80 (100) |
Eroglu, 20 0622 | Eastern Mediterranean | II-2 | Fair | CuT380A | Mixed | Vaginal | 12 mo | 268 | 268 | 257 (96) |
Goldthwaite, 201753 | North America | II-2 | Fair | Mixed | Immediate | Vaginal | 12 wk | 123 | 123 | 96 (78) |
Gueye, 201317 | Africa | II-3 | Fair | CuT380A | Immediate | Cesarean | 6 mo | 46 | 46 | 39 (85) |
Gupta, 201 423 | Southeast Asia | II-3 | Fair | CuT380A | Immediate | Mixed | 6 mo | 100 | 100 | 92 (92) |
Hayes, 200742 | North America | II-3 | Fair | LNG-IUS | Immediate | Vaginal | 10 wk | 20 | 20 | 16 (80) |
Heller, 201754 | Europe | II-3 | Fair | Mixed | Immediate | Cesarean | 12 mo | 120 | 114 | 99 (87) |
Hooda, 201 624 | Southeast Asia | II-2 | Poor | CuT380A | Immediate | Mixed | 6 wk | 593 | 593 | 171 (29) |
Jatlaoui, 201414 | North America | II-3 | Fair | Mixed | Immediate | Vaginal | 6 mo | 99 | 99 | 88 (89) |
Kumar, 201 425 | Southeast Asia | II-3 | Poor | CuT380A | Mixed | Mixed | 6 wk | 2,733 | 2,733 | 1,730 (63) |
Laes, 197555 | Europe | II-3 | Poor | CuT200 | Early | Unknown | 12 mo | 197 | 197 | 197 (100) |
Lavin, 198356 | South America | II-3 | Poor | CuT200 | Early | Unknown | 12 mo | 1,142 | 1,142 | 945 (83) |
Lester, 20158 | Africa | I | Poor | CuT380A | Mixed | Cesarean | 6 mo | 68 | 52 | Unknown (90#) |
Letti Muller, 200526 | South America | II-2 | Fair | CuT380A | Immediate | Mixed | 1 mo | 38 | 38 | 37 (97) |
Levi, 201227 | North America | II-3 | Fair | CuT380A | Immediate | Cesarean | 6 mo | 90 | 90 | 42 (47) |
Levi, 20157 | North America | I | Good | Mixed | Mixed | Cesarean | 6 mo | 112 | 87 | Unknown (88#) |
Mishra, 201433 | Southeast Asia | II-3 | Poor | CuT380A | Immediate | Mixed | 4–6 wk | 564 | 564 | 434 (77) |
Nelson, 200928 | North America | II-3 | Fair | CuT380A | Immediate | Cesarean | 6 wk | 7 | 7 | 7 (100) |
Newton, 197758 | Europe | II-3 | Poor | Cu7 | Immediate | Vaginal | 6 wk | 123 | 123 | 123 (100) |
Puzey, 200543 | Africa | II-3 | Poor | LNG-IUS | Immediate | Cesarean | 6 mo | 33 | 33 | 20 (61) |
Ragab, 201529 | Eastern Mediterranean | II-3 | Fair | CuT380A | Immediate | Cesarean | 12 mo | 40 | 40 | 40 (100) |
Shukla, 201257 | Southeast Asia | II-3 | Poor | CuT200 | Immediate | Mixed | 6 wk | 1,317 | 1,317 | 1,037 (79) |
Singal, 201430 | Southeast Asia | II-3 | Fair | CuT380A | Immediate | Cesarean | 12 mo | 300 | 300 | 300 (100) |
Singh, 20 1 631 | Southeast Asia | II-3 | Fair | CuT380A | Mixed | Vaginal | 8 wk | 80 | 80 | 80 (100) |
Soon, 201848 | North America | I | Poor | LNG-IUS | Mixed | Vaginal | 6 mo | 11 | 8 | 7 (88) |
Stuart, 201244 | North America | II-3 | Fair | LNG-IUS | Early | Vaginal | 6 mo | 40 | 29 | 27 (93) |
Stuart, 201545 | North America | I | Poor | LNG-IUS | Mixed | Vaginal | 6 mo | 35 | 31 | Unknown (80#) |
Sucak, 201532 | Eastern Mediterranean | II-2 | Fair | CuT380A | Immediate | Mixed | 12 mo | 160 | 160 | 153 (96) |
Turok, 201749 | North America | I | Poor | LNG-IUS | Mixed | Mixed | 8 wk | 285 | 228 | 214 (94) |
Unal, 201837 | Eastern Mediterranean | II-3 | Fair | CuT380A | Immediate | Cesarean | 3 mo | 70 | 70 | 68 (97) |
Whitaker, 201446 | North America | I | Poor | LNG-IUS | Mixed | Cesarean | 12 mo | 42 | 37 | Unknown (81#) |
Woo, 201510 | North America | II-3 | Poor | Mixed | Immediate | Mixed | 12 mo | 76 | 76 | 43 (57) |
Xu, 199934 | Western Pacific | II-3 | Fair | CuT380A | Immediate | Vaginal | 36 mo | 384 | 384 | 381 (99) |
Zerden, 201747 | North America | II-3 | Fair | LNG-IUS | Early | Mixed | 6 mo | 50 | 50 | 43 (86) |
IUD, intrauterine device; Cu, copper; LNG-IUS, levonorgestrel intrauterine system.
Based on World Health Organization regions with region of the Americas separated into North and South American regions.
Level of evidence: I, a randomized, controlled trial; II-2, a cohort or case-controlled study that includes a comparison group; III, an uncontrolled descriptive study including case series.
Defined by U.S. Preventive Services Task Force (Harris RP, Helfand M, Woolf SH, Lohr KN, Mulrow CD, Teutsch SM, et al. Current methods of the U.S. Preventive Services Task Force: a review of the process.
Mixed=CuT380A and LNG-IUS combined.
Immediate=10 min or less after placental delivery; Early=greater than 10 min to less than 4 wk postpartum; Mixed=Immediate and early placements or, immediate or early placements and interval placements (4 wk or greater postpartum).
Mixed=vaginal or cesarean delivery.
Number of women with IUDs placed having follow-up not reported; therefore, percentage represents number of women with IUD placements among all women randomized.