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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Acta Biomater. 2019 Apr 4;90:205–216. doi: 10.1016/j.actbio.2019.04.015

Fig. 2.

Fig. 2.

Performance of polymer-particle composite surgical sealants is enhanced by incorporating silica particles. (A) Schematic representation of direct deposition of polymer composite fibers onto a target organ. (B) Average burst pressures measured for different surgical sealants. Asterisk indicates statistically significant difference (p < 0.01) between the groups. Scanning electron microscope (SEM) images of intestinal tissue-sealant interface for (C) PLGA, (D) PLGA/PEG, and (E) P-620. Orange arrows indicate voids between the polymer and porcine intestinal tissue. Light blue arrows indicate silica particles at the interface between polymer and tissue. Scale bars = 50 mm for main image, 5 mm for inset. Composite surgical sealants are denoted “P-X”, where “X” is the diameter of the silica particles incorporated into PLGA/PEG. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)