Table 2.

Secondary outcomes of interest

Endpoint and definitions	Data source
Mortality outcomes
Inpatient mortality	Hospital record
Dialysis outcomes
Inpatient dialysis	Order entry system
Discharged on dialysis	Social work records
Renal failure outcomes
Percent who progress to Stage 2 AKI	Laboratory values
Percent who progress to Stage 3 AKI	Laboratory values
Duration of AKI	Laboratory values
Readmission rate and costs
30-day readmission rate	Hospital record
Cost of index hospitalisation	Billing records
Individual ‘Best Practice’ outcomes (proportion achieved per patient in study arm during index hospitalisation)
Contrast administration	Order entry system
Fluid administration	Order entry system
Aminoglycoside administration	Order entry system
NSAID administration/cessation	Order entry system
ACE inhibitor administration/cessation	Order entry system
Urinalysis order	Order entry system
Documentation of AKI	Postdischarge ICD-10 codes
Monitoring of creatinine	Order entry system
Monitoring of urine output	Hospital Record
Renal consult	Direct chart review
Provider awareness outcomes
Chart documentation of AKI (by post discharge ICD-10 codes)	Billing records
Chart documentation of AKI (adjudicated)	Direct chart review

ACE, angiotensin converting enzyme; AKI, acute kidney injury; NSAID, non-steroidal anti-inflammatory drug.