Table 1.
Significant enriched KEGG pathways of DEGs in ES dataset GSE12102
| Pathway | Count | P-value | Gene list |
|---|---|---|---|
| Mismatch repair | 5 | 5.00E-07 | MSH2, MSH6, RFC2, RPA2, SSBP1 |
| Spliceosome | 10 | 4.80E-04 | BUD31, DDX23, PPIH, PPIL1, RBMXL1, SNRNP200, SNRPA1, SNRPD1, SNRPE, WBP11 |
| Arginine and proline metabolism | 5 | 2.70E-03 | ALDH4A1, AMD1, OAT, ODC1, SMS |
| ABC transporters | 4 | 0.01 | ABCA1, ABCB4, ABCC1, ABCC6 |
| Cysteine and methionine metabolism | 4 | 0.01 | AMD1, DNMT3A, MPST, SMS |
| Sulfur relay system | 2 | 0.01 | MOCS2, MPST |
| Tryptophan metabolism | 4 | 0.01 | ACAT2, AFMID, CCBL2, INMT |
| Ubiquinone and other terpenoid quinone biosynthesis | 2 | 0.02 | COQ3, VKORC1L1 |
| Pentose phosphate pathway | 3 | 0.03 | FBP1, PGD, TALDO1 |
| Glutathione metabolism | 4 | 0.04 | GSTK1, ODC1, PGD, SMS |
Abbreviation: KEGG, Kyoto encyclopedia of genes and genomes.