Table 3.

Detailed research planning

Task	Calendar
	2017			2018												2019												2020
	T4			T1			T2			T3			T4			T1			T2			T3			T4			T1			T2			T3
Cohort recruitment and follow-up
Area preparation
Inclusion
Follow-up
Biological samples organisation
Parasite factors
Parasite whole genome sequencing
Parasite RNA-sequencing
Mass spectrometry analysis
Identified protein validation
Protein’s role on endothelium activation
Host factors
Macrophage M2 kinetics apparition in mice brain
Endogenous mediator role in neuroinflammation
Neuroinflammation markers identification in cerebral malaria patients
Results exploitation
Database validation
Data analysis
Dissemination