Figure 2.

Low ARID1A expression was associated with advanced TNM stage and poor prognosis in NPC patients. (A) Representative images of ARID1A expression in NPC biopsies with different TNM stages. High expression of ARID1A was observed for the T1, N0, M0, and I stage and DNKC subtype NPC biopsies, while low expression of ARID1A was detected for the T4, N3, M1, and IV stage and UDC subtype tumors. (B) Numbers and percentages of cases with high or low expression of ARID1A according to different clinicopathological features. (C) Low ARID1A expression was associated with a poor prognosis in NPC patients. *P<0.05, **P<0.01, ^#P<0.001.

Abbreviations: NPC, nasopharyngeal carcinoma; ARID1A, AT-rich interacting domain-containing protein 1A; DNKC, differentiated nonkeratinized squamous carcinoma; UDC, undifferentiated nonkeratinized carcinoma.