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. 2019 May 30;12:4287–4295. doi: 10.2147/OTT.S195853

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© 2019 Liu and Du.

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FENDRR overexpression inhibits the progression of colon cancer cells in vitro.

Notes: (A) qRT-PCR analysis of FENDRR expression in SW620 and Hct116 cells stably overexpressing FENDRR. (B) The effect of FENDRR overexpression on cell viability was evaluated by CCK-8 assay. (C) A colony formation assay was performed to assess the impact of FENDRR overexpression on cell proliferation. (D) The impact of FENDRR overexpression on cell invasion was assessed using transwell chambers with Matrigel. (E) Western blot analysis of epithelial–mesenchymal transition (EMT)-related markers expression in colon cancer cells after overexpression of FENDRR. *p<0.05, **p<0.01, ***p<0.001.