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Primary Care Respiratory Journal: Journal of the General Practice Airways Group logoLink to Primary Care Respiratory Journal: Journal of the General Practice Airways Group
letter
. 2011 Mar 22;20(3):336–337. doi: 10.4104/pcrj.2011.00021

Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome: a pilot study

Kazuhiko Kotani 1,2,3,*, Satoshi Kimura 4, Ichiro Komada 5, Naoki Sakane 1, Alejandro Gugliucci 2
PMCID: PMC6549841  PMID: 21431274

Abstract

Nasal continuous positive air pressure (nCPAP) treatment may favourably affect serum levels of advanced glycation end products (AGEs) in patients with obstructive sleep apnoea syndrome (OSAS). At baseline, OSAS patients had significantly higher levels of AGEs than controls. Six months after nCPAP initiation, AGEs decreased significantly. nCPAP treatment could lower AGEs in patients with OSAS.

Keywords: oxidative stress, advanced glycation, AGE, sleep apnoea, nasal CPAP

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Footnotes

There are no conflicts of interest in relation to the research presented.


Articles from Primary Care Respiratory Journal: Journal of the General Practice Airways Group are provided here courtesy of Primary Care Respiratory Society UK/Macmillan Publishers Limited

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