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. 2019 May 29;10:1200. doi: 10.3389/fmicb.2019.01200

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Copyright © 2019 Born and Pfeifer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the p-vac region of Hbt. salinarum PHH1. The 14 gas vesicles genes are arranged in two oppositely oriented gene clusters. The expression is driven by the four promoters P_pA, P_pD, P_pF, and P_pO. The activity of P_pA and P_pD is enhanced by the endogenous activator GvpE. In presence of GvpD the amount of GvpE decreases leading to a reduced expression. The p-gvpACNO, p-gvpDE, and p-gvpF-M transcripts contain a 5′-UTR of 20, 72, and 169 nt, respectively.