FIG A2.
Individual and geometric mean steady-state palbociclib trough concentration (Ctrough) in Asian and non-Asian patients. Analysis included all patients with reported steady-state Ctrough data from day 14 of cycles 1 and 2 and under fed conditions at the time of pharmacokinetic sampling, regardless of antacid use. The diamonds represent the geometric mean of within-patient mean values of steady-state Ctrough, the circles represent individual of within-patient mean values of steady-state Ctrough, and the dashed line represents the arithmetic mean of data from all patients. Box plots provide median and 25%/75% quartiles with whiskers to the last point within 1.5 times the interquartile range.