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. Author manuscript; available in PMC: 2019 Jun 5.
Published in final edited form as: Adv Exp Med Biol. 2017;953:209–306. doi: 10.1007/978-3-319-46095-6_6

Fig. 10.

Fig. 10

The organizer experiment of Spemann and Mangold. (a) Diagrammatic model of Spemann and Mangold’s dorsal lip transplantation from a lightly pigmented species (light gray) to the ventral region of a darker species (dark gray). (b) Image of a Xenopus tadpole following the successful grafting of an early gastrula dorsal lip, showing the endogenous axis (1° axis) and the induced partial axis (2° axis). The dark pigment in the head of the 2° axis is related to abnormal head development in the induced axis. (c) Diagram of a cross section through an embryo resulting from a dorsal lip transplant as in (a). The typical lineage contribution of the donor lip is lightly shaded reflecting the species origin, indicating contributions to the notochord, floor plate and medial somite (c is after Spemann and Mangold 1924). v ventral, d dorsal