Table 2.
Association between ambient exposure to particulate matter <2.5 μm in diameter (PM2.5) and antral follicle counts (AFC) among 632 women in the EARTH Study.
| Unadjusted % Change in AFC | Adjusted % Change in AFCa | |
|---|---|---|
| 3 Months Prior to AFC | ||
| Per 2 μg/m3 increase in PM2.5 | −7.2 (−9.4, −5.0) | −7.2 (−10.4, −3.8) |
| Quartiles of PM2.5 | ||
| Q1 (5.4–7.6 μg/m3) | REF | REF |
| Q2 (7.7–8.6 μg/m3) | −4.0 (−9.5, 1.8) | −2.2 (−8.1, 4.2) |
| Q3 (8.7–9.9 μg/m3) | −8.8 (−14.1, −3.2) | −5.5 (−11.8, 1.1) |
| Q4 (10.0–16.4 μg/m3) | −13.6 (−18.7, −8.2) | −9.0 (−16.3, −1.1) |
| 3 Months After the AFCb | ||
| Per 2 μg/m3 increase in PM2.5 | −4.8 (−7.1, −2.4) | −1.4 (−5.0, 2.2) |
| Quartiles of PM2.5 | ||
| Q1 (3.9–7.6 μg/m3) | REF | REF |
| Q2 (7.7–8.5 μg/m3) | −9.2 (−14.6, −3.5) | −5.5 (−11.4, 0.9) |
| Q3 (8.6–9.9 μg/m3) | −4.6 (−10.2, 1.3) | −0.7 (−7.3, 6.3) |
| Q4 (10.0–16.8 μg/m3) | −12.3 (−17.5, −6.7) | −4.4 (−12.2, 4.0) |
| Per 2 year increase in age | −8.1 (−9.1, −7.2) | −8.0 (−8.9, −7.0) |
We obtained effect estimates using Poisson regression.
a
Adjusted models account for age (continuous), BMI (continuous), smoking status (ever, never), year of AFC (quadratic), season of AFC (Jan-Mar, Apr-Jun, Jul-Sept, Oct-Dec).
b
615 women were included in this analysis (17 women who had their AFC performed in late 2015 were excluded because they were missing more than 7 days of PM data).