Study	Reason for exclusion
Bakalianou 2008	No statistical adjustment to reduce the threat of selection bias.
Black 2007	No statistical adjustment to reduce the threat of selection bias.
Cowan 2016	Numbers too small for inclusion.
Crawford 1999	No statistical adjustment to reduce the threat of selection bias.
Curtin 1990	No statistical adjustment to reduce the threat of selection bias.
Fan 2016	No statistical adjustment to reduce the threat of selection bias.
Fanning 1999	No statistical adjustment to reduce the threat of selection bias.
Feuer 1990	No statistical adjustment to reduce the threat of selection bias.
Fishman 1995	No statistical adjustment to reduce the threat of selection bias.
Goldblum 1997	No statistical adjustment to reduce the threat of selection bias.
Kim 2017	No statistical adjustment to reduce the threat of selection bias.
Koss 1968	A report of 10 cases, but on review of the paper, 2 participants had melanoma, therefore only 8 participants had Paget's disease.
Lee 1977	No statistical adjustment to reduce the threat of selection bias.
Lee 2010	No statistical adjustment to reduce the threat of selection bias.
Long 2017	No statistical adjustment to reduce the threat of selection bias.
Louis‐Sylvestre 2001	No statistical adjustment to reduce the threat of selection bias.
Machida 2015	Systematic review
Martorell‐Calatayud 2009	Was only a case report.
Molinie 1993	No statistical adjustment to reduce the threat of selection bias.
Niikura 2006	No statistical adjustment to reduce the threat of selection bias.
Parashurama 2017	No statistical adjustment to reduce the threat of selection bias.
Parker 2000	No statistical adjustment to reduce the threat of selection bias.
Parmley 1975	Only comments on 7 participants with invasive Paget's disease, no data on the 10 non‐invasive so cohort too small.
Petkovic 2006	No statistical adjustment to reduce the threat of selection bias.
Pierie 2003	No statistical adjustment to reduce the threat of selection bias.
Roh 2010	No statistical adjustment to reduce the threat of selection bias.
Sawada 2018	No statistical adjustment to reduce the threat of selection bias. Numbers too small for inclusion.
Shaco‐Levy 2010	No statistical adjustment to reduce the threat of selection bias.
Shingleton 1970	Contained only 1 participant with biopsy‐confirmed Paget's disease.
Stacy 1986	No statistical adjustment to reduce the threat of selection bias.
Strempel 1958	Contained only 3 participants with biopsy‐confirmed Paget's disease.
Tanaka 2009	Contained only 7 participants with biopsy‐confirmed Paget's disease
Tebes 2002	No statistical adjustment to reduce the threat of selection bias.
Wang 2003	Case report only of use of imiquimod 5%.
Zawislak 2004	Case report only of photodynamic therapy.