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. 2019 Jun 5;14(6):e0217335. doi: 10.1371/journal.pone.0217335

Table 4. Sleep problems and quality of life at week -12 in the two groups.

Gabapentin Placebo p-Value
Mean (SD) Mean (SD)
MOS-Sleep 
Sleep disturbance 32.7±21.7 22.8±26.6 0.028
Snoring 49.7±33.4 46.2±41.3 0.759
Awakens short of breath or headache 16.1±25.5 5.0±12.6 0.032
Sleep adequacy 70.3±26.2 78.7±26.2 0.005
Day-time somnolence 35.9±22.5 24.2±20.1 0.126
Sleep problems Index 25.4±19.8 17.4±15.6 0.038
MOS-Sleep: optimal sleep n/N (%) n/N (%) 0.392
19/33 (57.6) 20/42 (47.6)
SF-12
Physical functioning 44.9±11.8 51.5±7.5 0.005
Role Physical 26.1±4.1 28.7±2.3 0.001
Role emotional 18.7±5.2 21.8±2.6 0.001
Mental Health 45.3±10.2 53.7±8.1 <0.001
Bodily pain 47.6±12.5 53.1±7.9 0.026
General Health 43.4±10.8 45.8±9.4 0.315
Vitality 50.9±10.7 54.8±9.4 0.105
Social Functioning 47.8±11.1 49.5±11.2 0.508
Summary Scale Physical 44.1±9.9 47.8±6.6 0.061
Summary Scale Mental 38.1±9.0 42.6±6.5 0.018

Abbreviations: SD: standard deviation; SF-12: Short-Form 12; MOS-Sleep: Medical Outcomes Study.