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. 2019 Jun 5;14(6):e0217819. doi: 10.1371/journal.pone.0217819

Fig 4. Dgki deletion does not alter sensitization or recovery in chronic inflammatory or neuropathic pain models.

Fig 4

Withdrawal latencies to heat in the Hargreaves assay for 7 days following injection of complete Freund’s adjuvant (CFA) into the plantar surface of the ipsilateral and contralateral hindpaws in male (A) and female (B) Dgki-/- and WT mice. BL = baseline. Response rates to von Frey filaments of the indicated forces in male (C,E) and female (D,F) Dgki-/- and WT mice at baseline (C-D) and 14 days after spared nerve injury (SNI) surgery (E-F) in the ipsilateral and contralateral hindpaws. The number of mice tested is indicated in parentheses. Graphs show mean ± SEM. *p<0.05.