Comorbidity |
No Decompensation (N=56,258,977) |
Decompensation (DKA or HHS) (N=516,805) |
Overall Diabetes (N=56,775,782) |
P |
|
N |
% |
N |
% |
N |
% |
|
Deficiency anemias |
13,090,106 |
(23.3%) |
133,256 |
(25.8%) |
13,223,362 |
(23.3%) |
<0.001 |
Rheumatoid arthritis/collagen vascular diseases |
1,497,235 |
(2.7%) |
7,800 |
(1.5%) |
1,505,035 |
(2.7%) |
<0.001 |
Chronic blood loss anemia |
810,377 |
(1.4%) |
8,768 |
(1.7%) |
819,145 |
(1.4%) |
<0.001 |
Congestive heart failure |
8,322,450 |
(14.8%) |
55,687 |
(10.8%) |
8,378,137 |
(14.8%) |
<0.001 |
Chronic pulmonary disease |
13,078,014 |
(23.2%) |
72,929 |
(14.1%) |
13,150,943 |
(23.2%) |
<0.001 |
Coagulopathy |
2,757,738 |
(4.9%) |
41,094 |
(8.0%) |
2,798,832 |
(4.9%) |
<0.001 |
Depression |
6,690,600 |
(11.9%) |
61,777 |
(12.0%) |
6,752,377 |
(11.9%) |
0.177 |
Diabetes, uncomplicated |
45,681,704 |
(81.2%) |
377,695 |
(73.1%) |
46,059,399 |
(81.1%) |
<0.001 |
Diabetes with chronic complications |
10,577,273 |
(18.8%) |
139,110 |
(26.9%) |
10,716,383 |
(18.9%) |
<0.001 |
Drug abuse |
1,348,913 |
(2.4%) |
35,594 |
(6.9%) |
1,384,507 |
(2.4%) |
<0.001 |
Alcohol abuse |
1,641,121 |
(2.9%) |
38,869 |
(7.5%) |
1,679,990 |
(3.0%) |
<0.001 |
Smoking |
13,075,129 |
(23.2%) |
121,624 |
(23.5%) |
13,196,753 |
(23.2%) |
<0.001 |
Marijuana abuse |
287,515 |
(0.5%) |
9,618 |
(1.9%) |
297,134 |
(0.5%) |
<0.001 |
Cocaine abuse |
359,180 |
(0.6%) |
8,933 |
(1.7%) |
368,113 |
(0.6%) |
<0.001 |
Amphetamine abuse |
67,186 |
(0.1%) |
3,029 |
(0.6%) |
70,215 |
(0.1%) |
<0.001 |
Hypertension |
41,230,228 |
(73.3%) |
281,275 |
(54.4%) |
41,511,503 |
(73.1%) |
<0.001 |
Hypothyroidism |
7,794,548 |
(13.9%) |
52,834 |
(10.2%) |
7,847,382 |
(13.8%) |
<0.001 |
Liver disease |
2,073,814 |
(3.7%) |
25,751 |
(5.0%) |
2,099,564 |
(3.7%) |
<0.001 |
Fluid and electrolyte disorders |
15,330,626 |
(27.3%) |
324,203 |
(62.7%) |
15,654,829 |
(27.6%) |
<0.001 |
Metastatic cancer |
1,118,587 |
(2.0%) |
6,430 |
(1.2%) |
1,125,018 |
(2.0%) |
<0.001 |
Other neurological disorders |
4,561,379 |
(8.1%) |
45,649 |
(8.8%) |
4,607,029 |
(8.1%) |
<0.001 |
Obesity |
10,979,282 |
(19.5%) |
68,225 |
(13.2%) |
11,047,506 |
(19.5%) |
<0.001 |
Paralysis |
1,768,423 |
(3.1%) |
14,960 |
(2.9%) |
1,783,383 |
(3.1%) |
<0.001 |
Peripheral vascular disorders |
5,713,320 |
(10.2%) |
38,172 |
(7.4%) |
5,751,492 |
(10.1%) |
<0.001 |
Psychoses |
2,679,865 |
(4.8%) |
35,757 |
(6.9%) |
2,715,622 |
(4.8%) |
<0.001 |
Pulmonary circulation disorders |
1,531,356 |
(2.7%) |
11,291 |
(2.2%) |
1,542,647 |
(2.7%) |
<0.001 |
Renal failure |
12,812,496 |
(22.8%) |
111,550 |
(21.6%) |
12,924,045 |
(22.8%) |
<0.001 |
Solid tumor without metastasis |
1,218,692 |
(2.2%) |
6,112 |
(1.2%) |
1,224,805 |
(2.2%) |
<0.001 |
Valvular disease |
2,373,648 |
(4.2%) |
12,959 |
(2.5%) |
2,386,607 |
(4.2%) |
<0.001 |
Weight loss |
2,488,940 |
(4.4%) |
47,405 |
(9.2%) |
2,536,345 |
(4.5%) |
<0.001 |
Dyslipidemia |
25,420,113 |
(45.2%) |
157,907 |
(30.6%) |
25,578,021 |
(45.1%) |
<0.001 |
Previous MI PCI CABG |
11,084,254 |
(19.7%) |
49,435 |
(9.6%) |
11,133,689 |
(19.6%) |
<0.001 |