Comparison 1. Antihypertensive drug therapy vs control in adults 60 years or older.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Total mortality	13	25932	Risk Ratio (M‐H, Fixed, 95% CI)	0.91 [0.85, 0.97]
2 Cause of cardiovascular mortality	11		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Fatal stroke	11	25763	Risk Ratio (M‐H, Fixed, 95% CI)	0.67 [0.54, 0.82]
2.2 Fatal CHD	10	24478	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.67, 0.91]
3 Cardiovascular mortality and morbidity	15	26747	Risk Ratio (M‐H, Fixed, 95% CI)	0.72 [0.68, 0.77]
4 Cerebrovascular mortality and morbidity	13	26042	Risk Ratio (M‐H, Fixed, 95% CI)	0.66 [0.59, 0.74]
5 Coronary heart disease mortality and morbidity	11	24559	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.69, 0.88]
6 Withdrawal due to adverse effects	4	11310	Risk Ratio (M‐H, Fixed, 95% CI)	2.91 [2.56, 3.30]